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Anti-HEV – IgG Enzyme Immunoassay (EIA)

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Accredited by the Standards Council of Canada to Laboratory no. 594 (ISO/IEC 17025)

Requisition Forms

Reference Details


Detection of IgG antibody to the Hepatitis E virus by enzyme immunoassay (EIA).

Test Category:
Hepatitis E virus (HEV)
Illnesses and Diseases:
  • Hepatitis E

Serum or plasma sample. Minimum volume required for serum or plasma – 0.5 mL.

Collection Method:

Collect blood in serum separator tubes (SST) or EDTA tubes.

Specimen Processing, Storage and Shipping:

Store samples refrigerated or frozen until shipped for testing.  Ship frozen on wet or dry ice.

Transportation of Dangerous Goods:

Shipping of specimens shall be done by a TDG certified individual in accordance with TDG regulations. For additional information regarding classification of specimens for the purposes of shipping, consult either Part 2 Appendix 3 of the TDG Regulations or section 3.6.2 of the IATA Dangerous Goods Regulations as applicable.


Patient Criteria:

Suspected Hepatitis E infection.

Accompanying Documentation:

Completed Viral Hepatitis and Bloodborne Pathogens requisition including sender name, address and telephone number.  Patient name or identifier (referring specimen lab #), date of birth, suspected exposure, test(s) requested.  Type of specimen and date collected.  If possible, include the clinical history and lab results that have already been done at local or provincial laboratories.



Methods and Interpretation of Results:

Microplate EIA, commercially available assay ((Wantai, Beijing Biological Pharmacy Enterprise Co., Ltd.), research use only (RUO)).  A positive anti-HEV result may be indicative of current or past infection. A laboratory confirmed case of acute HEV infection requires a combination of anti-HEV IgG and IgM. A single anti-HEV (+) result is more likely to be due to past infection. Very rarely, some patients with anti-HEV IgG but no anti-HEV IgM are viremic (HEV RNA positive by PCR) and satisfy the laboratory criteria for acute case.

Turnaround Time:

15 calendar days.Borderline samples that need to be repeated have an extended turnaround time of 21 calendar days. Urgent clinical specimens require contact with the laboratory prior to submission and have a turnaround time of 3 calendar days.



Phone #: (204) 789-6512
Fax: (204) 318-2222
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