Resistance Mechanisms<<Return to Search Results
Beta-lactamase or carbapenemase resistance mechanisms are tested by PCR.
- Urinary tract infection
Send cultures as growth on culture medium or in transport medium. Culture vessel should be leak-proof or sealed appropriately.
Shipping of specimens shall be done by a TDG certified individual in accordance with TDG regulations. For additional information regarding classification of specimens for the purposes of shipping, consult either Part 2 Appendix 3 of the TDG Regulations or section 3.6.2 of the IATA Dangerous Goods Regulations as applicable.
Completed Antimicrobial Resistance and Nosocomial Infections Requisition.
Gram negative organisms may include but are not limited to: most Enterobacterales, Acinetobacter sp., and Pseudomonas sp.
PCR based method. Results are compared to known standards. Beta-lactamases tested: blaTEM, blaSHV, blaCTX-M, blaOXA-1, blaFRI. AmpC tested: blaCMY-2. Carbapenemases tested: blaKPC, blaIMP, blaVIM, blaNDM, blaGES, blaOXA-48, blaNMC/IMI. In addition, the following colistin resistance genes are tested: mcr1/2, mcr-3.
6 calendar days.
- Mataseje LF, et al 2016. Carbapenemase-Producing Enterobacteriaceae in Canada: Results from the Canadian Nosocomial Infection Surveillance Program, 2010-2014. Antimicrob Agents Chemother. pii: AAC.01359-16.
- Liu Y-Y, Wang Y, Walsh TR, Yi L-X, Zhang R, Spencer J, Doi Y, Tian G, Dong B, Hunag X, Yu L-F, Gu D, Ren H, Chen X, Lv L, He D, Zhou H, Liang Z, Liu J-H, Shen J. 2015. Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular study. Lancet Infect Dis; dx.doi.org/10.1016/S1473-3099(15)00424-7.